The second messenger molecules cAMP and Ca2+ regulate a large number of eukaryotic cellular events. cAMP acts on protein kinases and Ca2+ works through a ubiquitous calcium‐binding protein, calmodulin. The two systems are not independent, however, but interact in several important fashions. These interactions, and, in particular, the modulation of the cAMP signal by two Ca2+/calmodulin‐regulated proteins, cyclic nucleotide phosphodiesterase and calcineurin, are described here.

There are themes in Wittgenstein's later work which are extremely radical. By ‘radical’ I mean both that they cut to the very root of crucial philosophical issues, and that they tend to be ignored by the established philosophical positions of the day. More specifically, these themes focus on the understanding of epistemological bedrock, and they lead in directions about which it is difficult to get a hearing in major philosophical circles.

Jerry H. Gill provides a fresh angle of interpretation for the philosophy of Ludwig Wittgenstein by exploring his use of metaphor, as well as the implications of this use for new insights into his view of language in particular and philosophy in general. The first part of the work catalogs the major metaphors in the Tractatus, the Philosophical Investigations, and On Certainty. The second part explores what these metaphors mean in the context of a broader interpretation of Wittgenstein—an approach (...) that has not been developed by other interpreters. (shrink)

There is good reason to believe that Paul Tillich would have objected to the title of this paper. Several years ago I heard him begin a lecture on ‘Religious Existentialism’ with the comment, ‘There is no such thing as Religious Existentialism because there is only Religious Existentialism’. Similarly, he might have objected to the present paper's title by suggesting that every search for knowledge is, consciously or unconsciously, a religious search.

Reasoning about religion would seem to involve both explicit and tacit factors. These latter are what Pascal had in mind when he spoke of the ‘reasons of the heart which the reason knows not of’. Moreover, these reasons of the heart are the more interesting by virtue of being at least the more difficult and perhaps the more crucial. In these pages I want to examine the notion of reasons of the heart from the angle provided by the insights of (...) Michael Polanyi. Space will not permit a review of the major features of Polanyi's crucial concept of tacit knowledge. 1 I shall simply introduce and explore certain of these features as they seem relevant to the main concern of the paper. I trust this can be done in such a way as to be both meaningful to the reader and fair to Polanyi. (shrink)

Explores the thought of twentieth-century philosopher Michael Polanyi.

In _Words, Deeds, Bodies_, Jerry H. Gill seeks to connect the thought of L. Wittgenstein, J. L. Austin, M. Merleau-Ponty, and M. Polanyi in relation to the intersection between language and embodiment.

In _Words, Deeds, Bodies_, Jerry H. Gill seeks to connect the thought of L. Wittgenstein, J. L. Austin, M. Merleau-Ponty, and M. Polanyi in relation to the intersection between language and embodiment.

In this critical assessment of postmodernism, philosopher Jerry H. Gill points out that, however insightful the critiques of the postmodernists, they did little or nothing to offer constructive approaches to overcoming the impasse that their criticism of modernism created. Gill turns to an earlier generation of twentieth-century philosophers who anticipated later postmodern trends but offered alternative approaches to the dilemmas of modernism regarding the nature of reality, knowledge, and language. In four major chapters, Gill shows how Alfred North Whitehead, (...) Ludwig Wittgenstein, Maurice Merleau-Ponty, and Michael Polanyi reinterpreted reality, meaning, the mind-body problem, and knowledge in refreshingly new ways. Essentially, these four thinkers provide us with a deeper understanding of postmodernism by viewing the nature of reality as interactive and open-ended, meaning as contextual and functional, the role of the body as integral and axial, and knowledge as dynamic and tacit. To tie together the main themes of his study, Gill concludes with a brief analysis of the key insights offered by J. L. Austin, especially his "linguistic phenomenology.". (shrink)

In this excellent survey of Native American worldviews, philosopher of religion Jerry H. Gill emphasizes the value of tracing the overarching themes and broad contours of Native American belief systems. He presents an integrated view to serve as an introduction to ways of life and perspectives on the world far different from those of the dominant Euro-American culture. Drawing on the scholarship of anthropologists and specialists in American Indian Studies, Gill brings together much original research in broad, accessible chapters. (...) He explores Native American origin stories, the special connotations given to spatial concepts such as the cardinal directions and the circle, the influence of the seasons and the cycles of life on different cultures, and clan and kinship systems. Separate chapters are devoted to key ceremonies and customs as well as to concepts of health, harmony, virtues, wisdom, and beauty. The final chapter considers the devastating effects on native peoples of the European incursion into North America. Gill discusses the reservation system, attempts at assimilation and resistance, the recent renaissance of American Indian cultures, and prospects for the future. A valuable appendix presents a representative sampling of Native American writings on beliefs and origin stories. This excellent introduction to the many diverse yet related American Indian worldviews will be a welcome resource for teachers of introductory courses in Native American Studies or philosophy of religion, as well as laypersons with an interest in native cultures. (shrink)

In 1956, Melvin M. Rader started a tradition of exploring life's "enduring questions" via classic and contemporary philosophical readings. Jerry Gill upholds this tradition in the sixth edition of this respected introductory text that addresses such fundamental concepts of philosophy as rationalism, idealism, and the social contract.

Reason and quest for revelation, by P. Tillich.--On the ontological mystery, by G. Marcel.--The problem of non-objectifying thinking and speaking, by M. Heidegger.--The problem of natural theology, by J. Macquarrie.--Metaphysical rebellion, by A. Camus.--Psychoanalysis and religion by E. Fromm.--Why I am not a Christian, by B. Russell.--The quest for being, by S. Hook.--The sacred and the profane; a dialectical understanding of Christianity, by T. J. J. Altizer.--Three strata of meaning in religious discourse by C. Hartshorne.--The theological task, by J. B. (...) Cobb.--Theology and objectivity, by S. A. Ogden.--Can faith validate God-talk? by K. Nielsen.--The logic of God, by J. Wisdom.--Mapping the logic of models in science and theology, by F. Ferré.--On understanding mystery, by I. T. Ramsey.--Teilhard de Chardin; a philosophy of precession, by E. R. Baltazar.--The nature of apologetics, by H. Bouillard.--Metaphysics as horizon, by B. Lonergan.--Deciding whether to believe, by M. Novak. (shrink)

A tracing of the dynamics of the relationship between Faith and Philosophy throughout Western intellectual history, following the dynamics of Tertullian’s ancient question: “What has Athens to do with Jerusalem?” In the conclusion the author presents his own approach to this question.

A comparison of the views of Kierkegaard, Wittgenstein, and Kazantzakis on the topic of transcendence. A fresh model for understanding this important yet complex notion is offered by the author.

It is well known that the heart of Merleau-Ponty’s philosophy is the role of the body in all human experience and knowing, including even in the use of speech. Thus it is appropriate that his philosophy of language revolves around the notion of gesture. This essay explores the ramifications of this understanding of language in relation to the “speech” of deaf people through “American Sign Language,” which represents language as gesture par excellence.

Gill contends that the seeming loss of transcendence, in favor of naturalism (or overcome by thinking of intangible reality as it mediates and is mediated by tangible reality. He draws on well-seasoned theories of reality, knowledge, ethics, and language. Cloth edition, $26.50 (unseen). Annotation copyrighted by Book News, Inc., Portland, OR.

This brief comment is a point-by-point response to some elements of Ron Hall’s review of my recent book, The Tacit Mode: Michael Polanyi’s Postmodern Philosophy.

This brief comment is a point-by-point response to some elements of Ron Hall’s review of my recent book, The Tacit Mode: Michael Polanyi’s Postmodern Philosophy.

This article explores the relationship between Wittgenstein (both early and late) andWhitehead, specifically regarding the different views of the relationship between language and reality in these two thinkers.

A critique of the standard definition of knowledge as "justified, True belief" on the grounds that since truth, As judged by human knowers, Is a function of the process of justifying beliefs, It is superfluous as a defining characteristic of knowledge. The works of william james and j l austin are drawn on.